All cheats for this game by platform:
Wii
Downloadable Punch-Out!! Cheats
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Regaining Health
Press [-] between rounds to have more health at the start of the next round.
Save Yourself from a K.O.
When you're KO'd and the animation starts, quickly press [1] and [2] repeatedly (Wiimote controls). If done right you'll get one more chance. This only works once per fight.
Unlock Character Audio
In Exhibition mode complete the 3 challenges on any character and unlock their audio gallery.
Unlock Donkey Kong for Exhibition
If you face Donkey Kong in Last Stand mode, you unlock him to fight for Exhibition mode.
Unlock Each Boxer's Intro in Gallery Mode
As you're progressing through the game, simply view each boxer's intro and it'll unlock in the gallery mode.
Unlock Headgear
Lose 100 times total in single player mode.
Unlock Circuits/Modes
Major Circuit - Win the Minor Circuit Championship Title.
Last Stand Mode - Defeat Mr. Sandman in Title Defense Mode.
Title Defense Mode - Win the World Circuit Championship Title.
World Circuit - Win the Major Circuit Championship Title.
Regain Health After Knocking an Opponent Down
Alternatively tap the [1] and [2] buttons (or "drum" the remote and nunchuk) to regain health after knocking an opponent down.
Unlock Champions Mode
Win 10 bouts in Mac's Last Stand.