Arachnoman costume
Complete 90 City Events, collect 90 Tokens, and complete 48 combat tours.
Black costume
Complete 100 City Events, collect all 100 Tokens, and complete all combat tours.
Parker Hoodie costume
Complete 75 City Events, collect 75 Tokens, and complete 32 combat tours.
Peter Parker costume
Complete 50 City Events, collect 50 Tokens, and win the fourth race against Johnny Storm.
Spidey Wrestling costume
Complete 30 City Events and collect 30 Tokens.
Venom races
Complete all story mode missions.
Switch Hero option
Complete all story mode missions to unlock the "Switch Hero" option on the pause menu.
Medium city event difficulty
Complete 10 city events and "Inexpugnable" (Chapter 6).
Hard city event difficulty
Complete 20 city events and "Class Trip" (Chapter 8).
Medium combat tour difficulty
Complete 8 easy combat tours after "Hell of a Mess" (Chapter 4).
Hard combat tour difficulty
Complete 12 medium difficulty combat tours.
Insane combat tour difficulty
Complete all hard difficulty combat tours.
Defeating Rhino
Chase Rhino until you get to the wrecking ball site. Then, jump on his back by getting near him and pressing [X]. Pound on his back until you have his attention. Run over to the wet cement and have him do his punch attack there. His hand will get stuck in it. Go back to the wrecking ball as fast as possible and press [X] to have it hit Rhino. When you get to the battle scene after chasing him again, jump on his back as done earlier. Then, pound on him until his health is all the way down.
Defeating Silver Sable
When playing as Venom, you will encounter Silver Sable and must fight her. Repeatedly press [Y] when she is too close. When she is far away, throw cars at her. Feed on people until your life is full before you defeat her, as there is a difficult part afterwards.
Defeating Venom
During the last time you fight Venom (when he is trying to kill Trask), hit him while he is hitting the helicopter. When you get his attention, webzip to one of the two nearby buildings. He will try to hit you; every time he roars, come down and strike.
Defeating Wolverine
As Venom, keep on pressing "Tentacle".
Avoid falling damage
If you cannot web swing when you fall off a building, double jump just when you are about to hit the ground.
Fight Shocker again
You can see Shocker even after you have defeated him. Sometimes in a City Event, Shocker will appear and you must fight him. It will not be a Boss battle, though -- just a fight against a street thug, who has some very powerful blasters. Note: He is also stronger than all street thugs.
See Boomerang
Boomerang can also appear in a City Event.
Destruction game
When in free-roam as Venom, you can play a very fun game. After you cause a lot of destruction, a wave of policemen will appear. After you defeat them, a wave of S.H.I.E.L.D. Agents will appear. The next wave of enemies are Helicopters. Note: The S.H.I.E.L.D. Agents will stay. The final wave of enemies are S.H.I.E.L.D. Paratroopers. The S.H.I.E.L.D. Agents will still stay. You will also collect "points" throughout the destruction. Every enemy defeated gives you fifty "points".
Arachnoman billboard
When you are near the Empire State Building, you will see a billboard that shows Arachnoman Note: This is one of the costumes that you can get.
Venom: Secret move
As Venom, if the enemy is far away press [Y], [X]x2. If the enemy is close, press [B], [X]. If done correctly, Venom will grab the enemy and snap their spine. It will make a loud crunching noise. You can also press [Y] or [B] multiple times before pressing [X] to cause more damage. Snapping their spine usually causes a instant kill.
Wallrun
Get close to a building, then jump. Once you start going down the building, move the [Left Analog-stick] toward the wall, then press [X]. Spider-Man will Wallrun for a few of seconds then start Wall Crawling. Note: You cannot Wallrun down a building.
City repairs
After you complete Story mode, swing (or jump) around the city. You will see things like Rhino's foot prints, holes in the walls with a gate over them, etc. Note: If you do not see them as Spider-Manm switch to Venom.
Trouble levels
Level 1: Cops
Level 2: Cops with more health
Level 3: Helicopters
Level 4: Unknown
Level 5: Cops with more health coming out of helicopters
Balloon
In the first level available as Venom, when you feed on the kid and his balloon goes in the air, try to catch it. If you do, Venom will grab it and run around with it.
Ferris Bueller's Day Off reference
Toward the beginning of the game where Spider-Man has to go to school (and just before the race with the Human Torch) wander around the city and explore. Spider-Man will make comments like, "I need to get to class" and "I really have to get to school." One comment is something along the lines of, "I cant miss anymore class. I've been absent nine times... nine... times." This is in reference to a scene from the movie Ferris Bueller's Day Off in which the principal is taking note of the main character's habit of skipping class.
Glitch: Venom is Spider-Man
Go around as Venom and eat people, throw cars, etc. as usual. When the police are chasing you in the mini-game, go to "Unlockables" in the start menu. You will exit the mini-game. People will no longer run from you, and the police will not chase you. Note: Once you change to Spider-Man then go back to Venom, you must do this again. Also, you can fall into water and still destroy things.
Glitch: Falling Venom
As Venom, get close to a building. Super Jump up the building until you reach the top. When you are almost to the top, press [X] to grab the wall. Venom will fall backwards and land on his feet. This can be done with any building, but small buildings are recommended.
Glitch: Car in building
As Venom (usually after story mode is completed) grab a car. You must be close to the building. Aim the car at the building and throw it. If done correctly, the car will fly through the wall and explode. If it does not explode, use your tentacle attack toward the building. Your tentacles will hit the car and cause it to explode. Note: You can also knock people into the building.
Glitch: Civilian in ground
As Venom, go to Central Park. Once there, find the small bridge above the water. Stand under the bridge. In a few seconds someone will run by and fall through the ground. You can see them running around down there because the four arrow targets will still be on them.
Glitch: Invisible platform
As either Spider-Man or Venom, go near the Arachnoman billboard. Past that on the same side of the street is a blue building. Climb up it. You will see a little platform sticking out. Jump a few feet in front of it (but not too far), and you will be standing in mid air. You can also crawl on the bottom of the invisible platform.